Frequently Asked Questions
CBD is an acronym for cannabidiol, which is an active compound that occurs naturally in the hemp and cannabis plants. There are more than 545 compounds in the plants. CBD is a phytocannabinoid or cannabinoid for short, and scientists have isolated 144. Delta-9-tetrahydrocannabinol (THC) and CBD are the most known, but other compounds are showing promise, such as cannabigerol (CBG), which, like CBD, doesn’t have any psychoactive properties.
CBD was first isolated in 1940 by Roger Adams and colleagues, from a cultivar they referred to as “Minnesota Wild Hemp.” Further study in the early 1960s by Raphael Mechoulam, the father of modern cannabis research, found the compound was similar to THC, without the feelings of euphoria. Research is still on-going nearly 60 years after Mechoulam’s initial discoveries with scientists focusing on CBDA, the acidic precursor to CBD, which might offer the same benefits of CBD at higher doses. How does CBD work? It’s common for consumers to ask, “What is CBD?” and how it works before purchasing Horixen’s superior CBD products. Cannabinoids interact with the endocannabinoid system (ECS), which is a complex cell-signaling system found in the bodies of all vertebrates that helps regulate and maintain homeostasis among the body’s systems. The ECS is made up of three main parts:
- Cannabinoid Receptors (interact with the cannabinoids)
- Endocannabinoids (Endogenous or internal cannabinoids the body produces)
- Metabolic enzymes (to breakdown the endocannabinoids after they are used)
Research indicates the ECS plays a roll in the regulation of sleep, pain, memory, cardiac function, bone growth, GI function, and many other areas. This is because the cannabinoid receptors are found throughout the body with the highest concentration in the central nervous system.
So, what role does the CBD play? Cannabidiol is a phytocannabinoid that interacts with the ECS in the same way as endocannabinoids. The difference between how THC and CBD interact with the ECS may explain why one compound displays psychoactive effects, and the other doesn’t. THC doesn’t bind with the cannabinoid receptors, which is why it stays in the body longer. Whereas, CBD metabolizes in the liver.
After learning “What is CBD,” it’s easier to understand the potential benefits of the cannabinoid. There are thousands of research publications about CBD oil effects and its potential benefits. One reason why there are so many more reports about cannabidiol than the other cannabinoids is the lack of psychoactive effects it exhibits. There have been enough clinical trials for the FDA to approve Epidiolex, a plant-based CBD medication, to treat children two and older with severe forms of epilepsy that don’t respond to traditional seizure therapies.
The premium CBD oil cultivated at GW Pharmaceuticals’ indoor grow labs in the UK and imported to the U.S. at a price starting at nearly $40,000 per year for each patient. (There isn’t a specific price because the cost is calculated by weight.)
With the recent changes in hemp cultivation laws and the growing availability of CBD-based products, more reliable, scientific evidence will be available in the very near future.
In the meantime, the promising information government officials and medical professionals have available through anecdotal reports (verbal or written testimonials from patients, caregivers, practitioners), case studies involving mice, and the few human clinical trials are enough for the U.S. and several countries around the world to allow the legal sale of CBD oils and creams.
It’s important to only purchase cannabidiol oil from trusted sources. Our quality hemp is grown from non-GMO seeds, and each product goes through strict third-party testing to verify the quality and safety. Quality issues can vary from the type of oil. For example, there is a big difference between hemp seed oil and CBD oil.
Hemp seeds have tons of nutritional benefits, but no medicinal value. Horixen is a superior CBD oil made with only top-quality hemp components. CBD is found in the roots, stalk, stems, leaves, and flowers, with the highest concentration of compounds found in the flowers. Always be wary of low-priced products that claim to be “CBD oil”, while they are nothing more than glorified hemp seed oil.
We only grow our hemp in Kentucky, where we can guarantee the safe cultivation of each plant. The state of Kentucky has some of highest-rated hemp in the country and the most acreage, even outgrowing Colorado in 2019 with 60,000 acres. The super crop grows best in warm weather and doesn’t need as much water as traditional rotational plants, making it the perfect vegetation to grow in the southern state.
Horixen’s superior CBD oil uses CO2 extraction, which is the safest method available. Also known as supercritical or subcritical extraction, this uses high-pressure CO2 and low temperatures to remove the CBD and other compounds out of the plant without contaminating the oil. You can verify that there are no contaminants from the CO2 processing in our products by viewing the certificate of analysis on our website.
CO2 processing is the most expensive extraction method. Other companies may use different, less-safe ways to remove CBD from their hemp plants and charge a lower price. However, you can’t put a price on the safety of any products that you ingest or put on your body. The current vaping crisis in America is proof that third-party testing is more than worth the price.
Yes—All Horixen CBD oils and creams are safe for consumers that can’t use products containing gluten. The safe extraction process only uses natural oils and doesn’t add any artificial flavorings or preservatives.
Yes—Our products are plant-based and all natural.
CBD oil can come as a single-compound or an isolate that only contains CBD or a whole-plant concentrate that contains all the compounds in the hemp plant, including terpenes, minor cannabinoids, and nutritious molecules such as amino acids, omega fatty acids, and vitamins which may provide additional positive characteristics.
Terpenes are organic hydrocarbons found in hemp and many other plants. There are more than 20,000 known terpenes and nearly 200 have been identified in hemp and cannabis. These produce the different aromas associated with the various hemp cultivars.
Like most types of vegetation, there are dozens of varieties of hemp plants that vary by the chemical composition of cannabinoids, terpenes, flavonoids, and other compounds. For example, the scent of orange or citrus indicates a high level of limonene, which is the second most abundant terpene found in hemp following myrcene.
All Horixen CBD products go through rigorous, third-party testing to verify purity. Hemp is an amazing crop that’s able to pull contaminants out of the soil and clean it. However, those chemicals can absorb into the plant. Hemp from outside the U.S. can be a dangerous problem because many areas that have been international suppliers in the past have land that’s contaminated with heavy metals and other toxins. The dangers associated with these tainted, globally-sourced products outweigh the positive CBD oil effects. This is why we take extra precautions to ensure our products are completely safe.
Each product contains a certificate of analysis completed by an independent, third-party lab that test for:
- Heavy metals (lead, cadmium, arsenic, and mercury)
- Physical contaminants (dirt, dust, hair, insect parts, and fecal matter)
- Residual solvents (acetone, ethanol, butane, and isopropanol)
- Microbial screenings (bacteria, mold, and other microorganisms)
Impurities can occur during cultivation, harvesting, processing, and packaging, which is why we include a certificate of analysis for batch—To prove to our consumers that they can trust our superior CBD oils and creams.
No—CBD doesn’t have the psychoactive effects like THC, the compound that’s most responsible for producing the euphoria or “high” associated with these plants. By law, CBD can only contain .3% of THC, which is not enough to cause any of the side effects associated with large doses of THC. Our products include between .1% and .2% of THC maximum.
CBD has little to no side effects for most people. Some consumers may experience fatigue, irritability, and nausea. Additionally, there are potential drug-to-drug interactions between cannabidiol and the blood thinner Coumadin (generic brand warfarin.) According to an article by Dr. Peter Grinspoon, a professor at Harvard Medical School and primary care physician, this interaction is like the one between coumadin and grapefruit juice (foods high in vitamin K.) It would help if you spoke to your medical professional before taking CBD products.
While there are no long-term studies for CBD, there are also no known reports of CBD causing dependence.
It’s essential to understand that CBD is derived from the hemp plant (sometimes referred to as “industrial hemp” for legal purposes), and while CBD is also a compound found in the “marijuana” plant, these are two different plants. The U.S. government defines cannabis as containing more .3% of THC.
Regarding the term “marijuana”, this is a slang term given to the cannabis plant in the early 1920s during the beginning stages of cannabis prohibition. Prior to the legislation that changed the legal status of the plant, it was common for physicians to prescribe tinctures for minor complaints such as headaches and muscle aches.
The 2018 Farm Bill removed hemp with less than .3% THC from Schedule 1 status, making it legal across the U.S. In August, the DEA reminded all local law enforcement agencies that CBD is legal to sell, purchase, possess, and use. The FDA is still compiling guidelines for CBD but has also confirmed that it is legal for adults ages 18 and older.
No, CBD is legal to purchase without a doctor’s consent. However, if you’re uncertain about the cannabinoid, consider speaking with your practitioner first.
This is possible, although unlikely—Although all Horixen premium CBD tinctures and pain relief creams contain .01% to .02%, which is less than .03% of THC as required by U.S. law, we can’t guarantee the minute trace of THC won’t show up on a drug screening.
The sublingual tincture absorbs through the membrane under the tongue and into the bloodstream and has an onset of 10 to 20 minutes. For the best results, don’t eat or drink anything for at least 15 minutes after administering a sublingual dose. You can also use CBD oil effects through oral ingestion by swallowing the dose or adding to food or drinks. The onset for ingestion will take longer than the sublingual method, which goes through the digestion process and takes about 45 to 90 minutes to work.
CBD oils are one of the most accurate methods of delivery because of bioavailability (how much of the substance gets into the body with each dose), and treatments are measured with a dropper.
For example, a 300mg bottle of premium CBD oil contains 12, 25mg doses, and 750mg is equal to 30 doses.
Yes—It’s perfectly safe to add CBD to any liquids hot or cold (We enjoy adding our Big Sky Vanilla CBD tincture into our morning coffee). Horixen CBD oil is available in Big Sky Vanilla, Glacier Mint, and Montana Huckleberry, with new flavors and products always being developed, and are an excellent addition to any beverage.
Topical applications are applied just like any over-the-counter pain ointment. You take a small amount and gently massage into the area, and the onset is about 30 to 45 minutes. These absorb into the top layer of skin. Unlike tinctures, they don’t absorb into the bloodstream. Keep in mind that there is still a small chance that a topical CBD can absorb into the bloodstream through a cut or scratch and cause a positive drug screening.
Always store CBD oils and creams away in a room temperature area, away from direct heat and sunlight. If you live in a home with children under 18, keep products in a safe location where they can’t access it. Most CBD oils and lotions are good for up to two years when stored properly.
Absolutely! For all orders under $100 we currently offer First Class Shipping through USPS which usually takes 3 days. For all orders over $100 we offer free 2 Day shipping via USPS as well. We also offer expedited shipping if you’d like to get your Horixen products soon! Shop today and take advantage of this great benefit! *Please keep in mind that due to issues out of our control with 3rd party carriers we cannot personally guarantee arrival dates and times. We also don’t control the weather! Thank you for shopping with Horixen.